Preserving Muscle While Losing Fat: Why Tirzepatide with Glycine Is Gaining Ground

At Modern Medical Spa, we are constantly evolving our approach to weight management with a focus on health, longevity, and body composition—not just the number on the scale.

One of the most powerful tools we use for weight loss is tirzepatide, a dual GIP and GLP-1 receptor agonist that has transformed the lives of patients struggling with obesity or insulin resistance. But as we help patients shed excess fat, we’re also mindful of an important concern: preserving lean muscle mass.

The Power of Tirzepatide

Tirzepatide works by enhancing insulin sensitivity, regulating blood sugar, and reducing appetite. Patients experience significant fat loss, often faster and more efficiently than with other medications. However, rapid weight loss can come with unintended consequences, including muscle wasting—especially in those who aren’t engaging in resistance training or consuming enough protein.

At Modern Medical Spa, we’re committed to minimizing these risks by enhancing our tirzepatide protocols with evidence-informed strategies. One of those is compounding tirzepatide with glycine.

Why Add Glycine?

Glycine is a naturally occurring amino acid involved in collagen synthesis, antioxidant production (via glutathione), and muscle metabolism. It plays a vital role in tissue repair, anti-inflammatory signaling, and metabolic balance. When combined with tirzepatide in a compounded formulation, glycine may help support lean muscle preservation, reduce inflammation, and improve overall treatment tolerability.

Benefits of Tirzepatide + Glycine:

• Supports lean muscle mass during fat loss

• Enhances collagen production and tissue integrity

• May reduce oxidative stress from rapid weight loss

• Helps maintain metabolic balance and energy

Our Muscle-Preservation Protocol

To optimize results and protect muscle mass, we offer:

• Tirzepatide compounded with glycine (when clinically appropriate)

• Personalized protein intake recommendations

• Lifestyle coaching that emphasizes strength training

• Optional support with creatine, BCAAs, or hormone optimization

We believe weight loss should empower, not deplete. By preserving muscle, we’re not only protecting metabolism—we’re helping you look and feel your best.

Is This Right for You?

Whether you’re struggling with stubborn weight, pre-diabetes, or metabolic changes related to aging, our team at Modern Medical Spa will work with you to design a comprehensive program that fits your goals. We take a whole-body approach that prioritizes natural aesthetics, vitality, and long-term health.

📞 Ready to learn more? Call us today at 509-392-5007 to schedule a consultation.

Modern Medical Spa — Voted Best in the Tri-Cities, where science meets artistry to help you feel confident in your skin.